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68 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Product Name Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C79H110FN11O26 Molecular Weight 1648
193 Purity (HPLC) >= 95% Solubility DMSO
Single isomer 6-FAM ethylenediamine
membrane-impermeable Halotag ligand
Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8)-PNP coumarin 68 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload
