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The Mal-Propionyl group may also improve retro-Michael addition stability during antibody conjugation
Product Name Val-Cit-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C28H48N6O9 Molecular Weight 612
Azide and alkyne groups do not react or interfere with other functional groups found in biological samples but conjugate to one another with high efficiency
38 SMILES Cl
Product Name Lenalidomide-5'-CO-PEG6-C2-amine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C28H43ClN4O10 Molecular Weight 631
DBCO-Hexanoyl-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg The Mal-Propionyl group may alsoSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing
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