(S,R,S)-AHPC-CO-C8-acid Pomalidomide 18 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCCl)C(C)(C)C)C=C1 Purity (HPLC)

18 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCCl)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

396 SMILES [N-]=[N+]=NCCCCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-O-PEG1-propargyl Synonyms Thalidomide-4'-O-PEG1-propargyl CAS Number 2098487-79-5 Related CAS Molecular Formula C18H16N2O6 Molecular Weight 356

233 SMILES CC(C)(C)OC(=O)NC1=C(O)CCC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

S)-AHPC-acetamido-O-PEG1-C2-amine HCl Synonyms CAS Number 2097973-72-1 Related CAS 2010159-60-9 (free base)

(S,R,S)-AHPC-CO-C8-acid Pomalidomide 18 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCCl)C(C)(C)C)C=C1 Purity (HPLC)Degrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name (S,R,S) AHPC CO C8 acid Synonyms CAS Number 2172819 77 9 Related CAS Molecular Formula C32H46N4O6S Molecular Weight 614. 8 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCCCC(O)=O)C(C)(C)C)C=C1